productdatasheet
CatalogNo.:11094
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.
DC-UbPisa26kDaubiquitin-likeproteinfromdendriticcellscomprisedof106aminoacids.TheubiquitindomaininDC-UbPshares28.6%identitywithubiquitin,butitdoesnothavetheconservedC-terminusGly-Glyofubiquitinrequiredforubiquitinization.DC-UbPisfoundincytoplasm(particularlyinmitochondria),andDC-UbPmRNAisexpressedinvarioustumorcelltypes,butnotinnormaladulthumantissues,whichsuggestsaroleforDC-UbPintumOrigenesis.Inaddition,DC-UbPappearstobedownregulatedduringcellulardifferentiationandapoptosis.
LiuS,etal.2003BiochemBiophysResCommun300:800-805.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
SPECIFICATIONSUMMARYImmunogen:Syntheticpeptidecorrespondingtoaminoacids
197-212(SGRPLTDKMKFEELKI)of
humanDC-UbPprecursorconjugatedtoKLHattheN-terminus.Thissequenceis93%identicalwiththoseofmouseandratDC-UbP.
HostSpecies:Rabbit
StABIlizers:NonePreservatives:None.Availableonrequest.
Thisantibodyrecognizeshuman,mouse,andratDC-UbP.
ELISA:1:1,000-1:10,000withDc-UbP
onthesolidphase.Theinvestigatorshoulddeterminetheoptimaldilutionfortheirapplication.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
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