productdatasheet
CatalogNo.:11200
Size:50ugpeptideimmunogenaffinitypurifiedantibodyinPBScontaining0.02%sodiumazide.
p21-ActivatingKinase2(PAK2)functionsintheregulationofthebiochemistryandmorphologyofapoptoticcells.Thisproteinisactivatedthroughproteolyticcleavagebycaspase3inresponsetoavarietyofstresses,includingDNAdamage,hyper-osmolarity,additionofsphingosine,serumstarvation,andcontactinhibition.ActivatedPAK2actsonseveraltargetsincludinghistoneH4,myelinbasicprotein,ribosomalproteins6,andthenon-receptorproteintyrosinekinasec-Abl.AtleastfourmRNAtranscriptvariantshavebeenreported.
Antigen:SyntheticpeptideconjugatedtoKLH.
HostSpecies:Rabbit
Preservatives:0.02%sodiumazide
ThisantibodyrecognizesanepitopenearthecarboxyterminusofhumanPKA2.
APPLICATIONSImmunoblotting,Immunohistochemistry:
Useat2.5ug/ml.
Brain,cortex:Formalin-fixed,paraffin-embedded
Skeletalmuscle:Formalin-fixed,paraffin-embedded
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableat4oC(short-term)and-70oC(long-term).
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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