Anti-RAIDD(CT)Antibody
CatalogNo.:2406
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.
AnovelcelldeathadapterhasbeenidentifiedanddesignatedRAIDD(RIP-associatedICH-1/CED-3-homologousproteinwithDD)andCRADD(caspaseandRIPadapterwithDD).RAIDDcontainsaDDandaCARD(caspaserecruitmentdomain)whichinteractwithRIPandcaspase,respectively,totransducedeathsignals.RAIDDisconstitutivelyexpressedinmanytissuesandmediatesapoptosiscausedbyFasandTNFR1.
Antigen:Syntheticpeptidecorrespondingtoaa181-199attheC-terminusofhumanRAIDD(accessionno.AAB42217).
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide.
Thisantibodyrecognizesfull-lengthhumanRAIDD(22kDa).
APPLICATIONSImmunoblotting:useat1ug/ml.
WesternblotanalysisofRAIDDinHeLacelllysatewithRAIDDantibodyat1μg/ml.
Positivecontrol:HeLacelllysate.
Immunohistochemistry:useat10ug/ml.
ImmunohistochemicalstainingofRAIDDinhumankidneywithRAIDDantibodyat10μg/ml.
Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortherapplications.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
