Anti-SAPKα(Stress-Activatedc-JunProteinKinaseα)Antibody
CatalogNumber | Quantity |
11050-25 | 25ul |
11050-100 | 100ul |
CatalogNumber | Quantity |
11050-25 | 25ul |
11050-100 | 100ul |
ORDERINGINFORMATION
Thestress-activatedproteinkinasesalphaandgamma(SAPKalphaandgamma),alsoknownasc-JunNH2-terminalkinases1and2(Jnk1/2)areserine/threonineproteinkinasesbelongingtotheMAPkinasefamily.ExtracellularstimulileADIngtocellstressincludeinflammatorycytokines(viaRhoandRac),growthfactors,proteinsynthesisinhibitorsandosmoticstress.BothJnk1andJnk2mustbeduallyphosphorylatedintheactivationloop,atthreonine183andtyrosine185,toachievefullenzymaticactivity.
Antigen:Syntheticpeptidecorrespondingtoaa1-16ofratSAPKα(MSDSKSDGQFYSVQVA(C)).
HostSpecies:Rabbit
Format:Wholeserum
Thisantibodyrecognizeshuman,mouse,andratSAPKα(55kDa).
APPLICATIONSImmunoblotting:useata1:500dilution.
WesternblotanalysisofSAPKαinmousebraintissueextractwithSAPKαantibodydiluted1:500.
Positivecontrol:Mousebraintissueextract.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
