productdatasheet
YersiniapestisVAntigenMonoclonalAntibodies
CatalogNumber | Size |
18772-200 | 200ug |
18773-200 | 200ug |
18774-200 | 200ug |
18775-200 | 200ug |
18776-200 | 200ug |
18772-1000 | 1mg |
18773-1000 | 1mg |
18774-1000 | 1mg |
18775-1000 | 1mg |
18776-1000 | 1mg |
CatalogNumber | Size |
18772-200 | 200ug |
18773-200 | 200ug |
18774-200 | 200ug |
18775-200 | 200ug |
18776-200 | 200ug |
18772-1000 | 1mg |
18773-1000 | 1mg |
18774-1000 | 1mg |
18775-1000 | 1mg |
18776-1000 | 1mg |
ORDERINGINFORMATION
Format:TheseantibodiesarepurifiedbyProteinGaffinitychromatographyandaresuppliedinPBS,pH7.4,containing0.1%sodiumazideaspreservative.
Y.pestis,thecausativeagentofplague,haslow-Ca+2response(LCR)virulenceplasmidsthatencodeasetofsecretedvirulenceproteinsincludingYersiniaouterproteins(YOPS)andtheVantigen,LcrV.SomeoftheYOPSplayaroleinadherencetoeukaryoticcellswhileothersaretargetedintoaeukaryoticcellatthesiteofadherence.TheYOPSderangecellularsignalingandcytoskeletalfunctionsnecessaryforhostdefensessuchasphagocytosis.LcrVisasecretedanti-hostcomponentwithdirectimmunomodulatoryeffects.LcrVexpressionisinvolvedintargetingofYOPStohostcellsandisrequiredforcytotoxicity.
SPECIFICATIONSUMMARYAntigen:Recombinantfull-length
Y.pestisVantigen.
HostSpecies:MouseAntibodyClass:AllareIgG1.Preservative:0.1%NaN3
Theseantibodiesspecificallyrecognize
Y.pestisVantigen.Theydonotcross-reactwithY.pestiscapsularF1antigen.
Immunoblotting:End-usershoulddetermineoptimalconcentration.Werecommendtestingaconcentrationrangeof1-10ug/ml.Abandof37kDaisdetected.
ELISA:End-usershoulddetermineoptimalconcentrationfortheirsample.SandwichELISA:use18772ascoatingantibodyand18773asdetectantibody.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat4oCor-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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