productdatasheet
CatalogNo.:3331
Size:100ugProteinG-purifiedantibodyinPBS,pH7.4
Antigen:PeptidecorrespondingtotheC-terminusofhumanAIB1conjugatedtokeyholelimpethemocyanin(KLH).
HostSpecies:MouseAntibodyClass:IgG1/κStABIlizers:None
Preservatives:None.Availableonrequest.
ThisantibodyrecognizeshumanAIB1,a160kDproteinandmemberoftheSRC-1familyofnuclearreceptorcoactivators.AIB1isamplifiedinbreasttumorsandpancreaticcancercelllines.AIB1interactswiththeestrogenreceptortoenhanceestrogen-dependenttranscriptionalgeneactivation.
APPLICATIONSImmunoblotting:useat1-5ug/ml.
Positivecontrol:MCF-7cells.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-70oC.Avoidmultiplefreeze-thawcycles.
Anzick,SLetal.1997.Science277:965-968;Bautista,Setal.
1998.ClinCancerRes4:2925-2929;GhADImi,BMetal.1999;AmJPathol154:525-536.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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