productdatasheet
CatalogNo.:34010
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.
NORE1,firstidentifiedbyitsABIlitytobindtoactiveRas,isrelatedinaminoacidsequencetothetumorsuppressorRASSF1.ExpressionofNORE1suppressescolonyformationbyA549andG361cells,inhibitsanchorage-independentgrowthbyA549cellsanddelaysA549progressionthroughG1withoutevidenceofincreasedapoptosis.NORE1suppressesthegrowthoftumorcelllinesindependentofRas-likeproteinsortheproteinkinasesMST1and2.
Immunogen:Syntheticpeptidecorrespondingtoaaresidues313-329(DNPQKFALFKRIHKDGQ)ofhuman
NORE1conjugatedtoKLH.HostSpecies:RabbitStabilizers:None
Preservatives:None.Availableonrequest.
SPECIFICITYThisantibodyrecognizeshuman,mouse,andratNORE1(approx47kDa).
Immunoblotting:useat1:500-1:1,000dilution.
Positivecontrol:Lysateof293TcellsexpressingNORE1.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
AoyamaYetal.(2004)Oncogene
23:3426-33.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
QEDBioscience,Inc.10919TechnologyPlace,SuiteC
SanDiego,CA92127
TollFree800.929.2114
Phone858.675.2405
Fax858.592.1509
info@qedbio.com
Visitourwebsiteforadditionalproductinformationandtoorderonline.
qedbio.com
