ADVANCEDRESEARCHTECHNOLOGIES
CatalogNo.:34037(clonePAb1801Size:100uginPBS,pH7.4;50%glycerol,0.09%sodiumazide.PurifiedbyProteinAaffinitychromatography.
p53isaDNA-binding,cellcycle-regulatingtranscriptionfactorthatgovernscelldivision.Itplaysacriticalroleintumorsuppressionandhasbeenreferredtoas“theguardianangelgene”or“themasterwatchman”.Defectsinp53arelinkedto
>50%ofhumancancersandrestoringp53functiontocancercellscaninducegrowtharrestandapoptosis.Damagedp53canalsoleadtoautoimmunedisorders.
Antigen:Fusionproteincorrespondingtoaa46-53ofhumanp53.
HostSpecies:Mouse
AntibodyClass:IgG1
Thisantibodyrecognizeshumanp53.
ELISA,Immunoblotting(1:1,000-1:2,000),
Immunohistochemistry(1:100-1:250),Immunoprecipitation(10ug/mg).
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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