productdatasheet
CatalogNo.:56224
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.
Antigen:Peptidecorrespondingtoaa2-17ofhumanp53R2.
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide
ThisantibodyrecognizesanepitopeattheN-terminusofhuman,mouse,andratp53R2,ap53inducIBLegenethatcontainsap53bindingsequenceandencodesasubunitoftheenzymeribonucleotidereductase.p53R2isinducedbyagentsthatcauseDNAdamage,suchasUVandγ-irrADIation.Theproductofthep53R2geneisdirectlyinvolvedinthep53checkpointforrepairofdamagedDNA.
APPLICATIONSImmunoblotting:useat0.5-1ug/ml.Inimmunoblots,abandof39kDisdetected.
Positivecontrol:A431celllysate.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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