productdatasheet
CatalogNo.:56213
Size:100ugProteinG-purifiedantibodyinPBS,pH7.4
Antigen:GSTfusionproteincorrespondingtothecompletecodingregion(aa1-425)ofRad50expressedinE.coli.
HostSpecies:MouseAntibodyClass:IgG1/κStABIlizers:None
Preservatives:None.Availableonrequest.
ThisantibodyrecognizeshumanRad50,a153kDproteininvolvedinDNAdoublestrandbreakrepair.Rad50isassociatedwithMre11andp95(Nibrin)toformamultiproteincomplex.FollowingDNAdamage,Rad50andMre11redistributeandareco-localizedwithinthenucleusofdamagedcells.
APPLICATIONSImmunoblotting,immunoprecipitation:useat0.1-2ug/ml.
Positivecontrol:Rajicells.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-70oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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