productdatasheet
CatalogNo.:34023
Size:50ugpeptideimmunogenaffinitypurifiedantibodyinPBScontaining0.02%sodiumazide.
p53R2isap53induciblegenethatcontainsap53bindingsequenceandencodesasubunitoftheenzymeribonucleotidereductase.p53R2isinducedbychemicalsandirrADIationthatcauseDNAdamage.Theproductofthep53R2geneisdirectlyinvolvedinthep53checkpointforrepairofdamagedDNA.Theisoformofthep53familymemberp73alsoinducesp53R2expression.P53R2isanimportanttargetofp53fortumorsuppression.
Antigen:SyntheticpeptideconjugatedtoKLH.
HostSpecies:Rabbit
Preservatives:0.02%sodiumazide
Thisantibodyrecognizesanepitopewithinaa2-17ofhumanp53R2.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
Immunoblotting:Useat0.5-1ug/ml.
Immunohistochemistry:Useat2.5ug/ml.
Tonsil:Formalin-fixed,paraffin-embedded
Brain,cerebellum:Formalin-fixed,paraffin-embedded
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableat4oC(short-term)and-70oC(long-term).
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