productdatasheet

CatalogNo.:34009

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.

AnovelgenecontainingSNF2,PHD-finger,RING-finger,helicase,andlinkerhistonedomainstermedSHPRH,isapossIBLecandidateforatumorsuppressorgene.ThesedomainsarecharacteristicofseveralDNArepairproteins,transcriptionfactors,andhelicases.Mappingofthisgeneto6q24,aregionreportedtocontainatumorsuppressorlocus,suggestsaroleforSHPRHintumorsuppression.

Immunogen:Syntheticpeptidecorrespondingtoaaresidues515-535(DKTKKQAVGSPRKIEKELRKS)of

mouseSHPRHconjugatedtoKLHattheN-terminus.

HostSpecies:Rabbit

StABIlizers:NonePreservatives:None.Availableonrequest.

ThisantibodyrecognizesmouseSHPRH(approx.185kDa)whichhas90%sequencehomologywithhumanand95%sequencehomologywithrat.

Immunoblotting:useat1:250dilution.

Positivecontrol:Mousebrainlysate.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

SoodR.etal.(2003)Genomics82:153-161.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.