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CatalogNo.:34025

Size:50ulascitesfluidcontaining0.05%sodiumazide.Antibodyconcentrationapprox.0.9mg/ml.

Telomeraseisareversetranscriptasethataddstelomericrepeats(TTAGGG)tochromosomeends.Innormalsomaticcells,telomeraseisnotactiveandtelomeresprogressivelyshorten,leADIngtolimitedcellLifespanandsenescence.Activationoftelomeraseisassociatedwithhumancancersandcellimmortalization.Humantelomeraseiscomprisedofthreemajorsubnunits:acatalyticsubunit(hTERT),atemplateRNA(hTR),andtelomerase-associatedprotein(TEP-1).TranscriptionofTERTistheprimarymechanismforregulatingtelomeraseactivity.

Antigen:Full-lengthrecombinanthTERTexpressedininsectcells.HostSpecies:Mouse

CloneNo.:2C4

AntibodyClass:IgM

Preservatives:0.05%sodiumazide

ThisantibodyrecognizeshumanTERT;specificepitopenotdetermined.

Immunoblotting:Useat1:500-1:1,000dilution.

Flowcytometry:Useat1:400dilution.Immunohistochemistry:Useat1:1,000dilution.

Pancreas:Formalin-fixed,paraffin-embedded

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableat4oC(short-term)and-70oC(long-term).

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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