productdatasheet
CatalogNo.:34028
Size:50ugimmunogenaffinitypurifiedantibodyinPBScontaining0.1%sodiumazide.
Tumorendothelialmarker5(TEM5)isamemberoftheadhesionfamilyofGPCRsandisupregulatedinendothelialcellsduringtumorandphysiologicangiogenesis.SolubleTEM5(sTEM5)isshedbyendothelialcellsduringangiogenesisandbindstoglycosaminoglycansonextracellularmatrixandcellsurfaceproteoglycans.Afterproteolyticprocessing,anRGD-bindingsiteforintegrinαvβ3isexposedonsTEM5.AdhesionofendothelialcellstoimmobilizedproteolyticallyprocessedsTEM5promotestheirsurvival.
Antigen:SyntheticpeptideconjugatedtoKLH
HostSpecies:Rabbit
Preservatives:0.1%sodiumazide
ThisantibodyrecognizesanepitopewithintheextracellulardomainofhumanTEM5.
APPLICATIONSImmunohistochemistry:Useat10ug/ml.
Coloncarcinoma:Formalin-fixed,paraffin-embedded
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableat4oC(short-term)and-70oC(long-term).
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
QEDBioscience,Inc.10919TechnologyPlace,SuiteC
SanDiego,CA92127
TollFree800.929.2114
Phone858.675.2405
Fax858.592.1509
info@qedbio.com
Visitourwebsiteforadditionalproductinformationandtoorderonline.
qedbio.com
