CatalogNo.:13020
Size:100ugIgG(1mg/ml)inTris-citrate/phosphatebuffer,pH7-8.
BRD2(bromodomain-containing2)isanuclearmitogen-activatedkinasethatplaysaroleintranscriptionofcell-cycle-regulatedgenesbyfunctioningasanadapterproteinthatrecruitsE2FandchromatinremodelingfactorstoE2Fresponseelements.
Antigen:SyntheticpeptiderepresentingaportionoftheproteinbetweentheputativenuclearlocalizationsignalandtheETdomain
Accessionno.:NP_005095.1
GeneID:6046.
HostSpecies:Goat
StABIlizers:None
Preservatives:0.09%sodiumazide
ThisantibodyreactswithhumanBRD2.
Thespecificepitopeisintheregionbetweenaa550and600ofhumanBRD2.
Basedon100%sequenceidentity,thisantibodyispredictedtoreactwithBovine,RhesusMonkey,Gorilla,White-tufted-earmarmoset,Crab-eatingmacaqueandNorthernwhite-cheekedgibbon.
Antibodyisaffinity-purifiedwithanepitopespecifictoBRD2immobilizedonsolidsupport.
APPLICATIONSImmunoblotting:0.025–0.1ug/ml.
DetectionofhumanBRD2inRIPAextract(10ug)ofHeLacellsuntreated(-)ortreated(+)withcalfintestinalphosphatasewith#13020at0.05ug/ml.
DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.
Thisproductisstableat2-8°Cfor1year.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
