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CatalogNo.:13805

Size:50ugpeptideimmunogenaffinitypurifiedantibodyinPBScontaining0.1%sodiumazide.

Ceramidekinase(CERK),whichphosphorylatesceramidetoproduceceramide1-phosphate(C1P),wasfirstdescribedasaCa+2-stimulatedlipidkinasethatcopurifiedwithbrainsynapticvesicles.CERKactivityhasbeenreportedinHL60cells,mastcells,andneutrophils.CERKisinvolvedinphagolysosomeformationinplymorphonuclearleukocytesandalsoinliposomefusion.C1Phasbeenreportedtohavemitogeniceffects.

Morerecently,C1Pwasfoundtoinducearachidonicacidreleaseandprostanoidsynthesis.

Antigen:SyntheticpeptideconjugatedtoKLH.

HostSpecies:Rabbit

Preservatives:0.1%sodiumazide

ThisantibodyrecognizestheN-terminalextracellulardomainofhumanCERK.

Immunohistochemistry:Useat20ug/ml.

Braincortex:Formalin-fixed,paraffin-embedded.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableat4oC(short-term)and-70oC(long-term).

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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