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当前位置: 首页 > 产品中心 > cytokine > QED生物科学/FPR1/2单克隆抗体/30107/1 Ea
商品详细QED生物科学/FPR1/2单克隆抗体/30107/1 Ea
QED生物科学/FPR1/2单克隆抗体/30107/1 Ea
QED生物科学/FPR1/2单克隆抗体/30107/1 Ea
商品编号: 30107
品牌: qedbio
市场价: ¥6740.00
美元价: 4044.00
产地: 美国(厂家直采)
公司:
产品分类: 细胞因子
公司分类: cytokine
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍


FPR1/2MonoclonalAntibody


ORDERINGINFORMATIONCatalogno.:30107Cloneno.:NFPRaSize:100ugProteinG-purifiedantibodyinPBSpH7.4.


BACKGROUND

Formylpeptidereceptors(FPR)areGprotein-coupledreceptorsthatare

activatedbydifferentagoNISTsincludedN-formylatedpeptidesoriginatingfrombacteriaandmitochondria.Inhumans,theFPRfamilyincludesthehighaffinityFPR1,thelowaffinityFPR2/ALX(previouslyknownasFPRL1orALX)andFPR3.HumanFPR1isimportantforphagocytechemotaxis,superoxideproduction,anddegranulation,andhelpsdirectphagocytestositesofinfection.

FunctionalFPR1expressionhasbeendemonstratedonfibroblasts,bonemarrowmesenchymalstemcells,A549lungcells,HEP-G2hepatomacells,andonseveraltypesofepithelialcells.


SPECIFICATIONSUMMARYAntigen:His-taggedrecombinantFPR1(humanneutrophilN-formylpeptidereceptor1)expressedinandpurifiedfromSf9cells.HostSpecies:MouseAntibodyClass:IgG1APPLICATIONS

Immunoblotting:useat1-5ug/ml.

Alkali-strippedmembranesfromrFPR-expressingCHOcells(lane2)anddegranulatedhumanneutrophils(lane

3)blottedwith#30107.SeeRiesselmanM.etal(below)fordetails.

Immunofluorescence:useat10ug/ml.

Methanol-fixedhumanneutrophilsstainedwith#30107.SeeRiesselmanM.etal(below)fordetails.

Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplication.


DILUTIONINSTRUCTIONS

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisproductisstableforatleastone(1)

oo

SPECIFICITY

ThisantibodyrecognizeshumanFPR1ataa305-GQDFRERLI-313attheamino-terminalportionofthecarboxyl-terminaltail.ItalsorecognizesthesameepitopeinFPR2.


Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticapplications.

yearat-20Cto-70C.Storeproductin

appropriatealiquotstoavoidmultiplefreeze-thawcycles.


PRODUCTREFERENCES

RiesselmanMetal.2007JImmunol179:2520-2531.

MAATyWSetal.2013JBiolChem288:27042-27058.

品牌介绍
QEDBioscience已经设计和制造抗体超过20年,QEDBioscience的目标保持不变:提供市场上最好的抗体产品和服务,并为QEDBioscience的客户提供他们期望的全面的专业知识和帮助。频谱抗体公司如QED。QEDBioscience为我们的学术,生物技术,诊断和药物研究客户开发新型单克隆和多克隆抗体产品。QEDBioscience使用客户的小分子,蛋白质或肽靶标或利用靶CDNA开发这些抗体,是一家提供全方位服务的公司,并提供额外的免疫化学服务,如纯化和结合,以便我们能够为客户提供一种特异于其系统的抗体产品。我们还开发了具有酶中和和抑制受体-配体相互作用以及抗独特型抗体的药理活性的单克隆抗体。