CatalogNo.:11140(clone4H9-D7)Size:100uginPBS(1mg/ml),pH7.4,50%glycerol,0.09%sodiumazide.

PurifiedbyProteinGaffinitychromatography.

Aha1isamemberoftheHsp90co-chaperonefamilythatappearstostimulateHsp90ATPaseactivitybycompetingwithp23andotherco-chaperonesforHsp90binding.Aha1alsointeractswithHSPCA/Hsp90andwiththecytoplasmictailofthevesicularstomatitisvirusglycoproteins(VSV-G).Aha1isexpressedinnumeroustissuesincludingbrain,heart,skeletalmuscle,andkidneyandispresentatlowlevelsinliverandplacenta.

Antigen:His-taggedrecombinanthumanAha1(accessionno.

NP_036243.1)

HostSpecies:Mouse

AntibodyClass:IgG1

ThisantibodyrecognizeshumanandmouseAha1andcross-reactswithmouseAha2.

Immunoblotting:useat1ug/ml.Abandof

~38kDaisdetected.Bandcanappearashighas45kDa.

WesternblotdetectionofAha1in(1)HeLacellsandrecombinantAha1(H)with#11140at1ug/ml.

ELISA:useat1-10ug/mlwithAha1onthesolidphase.

Thesearerecommendedconcentrations;endusershoulddetermineoptimalconcentrationsfortheirapplications.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notintendedfordiagnosticortherapeuticapplications.