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当前位置: 首页 > 产品中心 > Functional_antibody > QED生物科学/Hsp70/11096/1 Ea
商品详细QED生物科学/Hsp70/11096/1 Ea
QED生物科学/Hsp70/11096/1 Ea
QED生物科学/Hsp70/11096/1 Ea
商品编号: 11096
品牌: qedbio
市场价: ¥4900.00
美元价: 2940.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍


Anti-Hsp70MonoclonalAntibody


ORDERINGINFORMATIONCatalogNo.:11096(cloneC92F3A-5)Size:100uginPBS,pH7.4,50%glycerol,purifiedbyProteinGaffinitychroma-tography.


BACKGROUND

Hsp70genes,membersofamultigenefamily,encodeheat-inducIBLe70kDaheat-shockproteinsthatfunctionasmolecularchaperones.Theyhavebeenidentifiedinmostorganellesofeukaryoticcellsaswellasinbacteria.TheN-terminusofHsp70bindsATPwithhighaffinityandtheC-terminusbindsproteinsandpolypeptides.Hsp70sbindnascentpolypeptidesaswellaspartiallyfoldedintermediatesofproteins,thuspreventingtheiraggregationand/ormisfolding.BindingofATPtriggersaconformationalchangethatresultsinthereleaseofboundprotein.Hsp70sfunctioninproteinsynthesis,proteinfoldingandoligomerization,andproteintransport.


SPECIFICATIONSUMMARYAntigen:HumanHsp70purifiedfromHeLacells.HostSpecies:MouseAntibodyClass:IgG1Preservatives:0.1%sodiumazide.


SPECIFICITY

ThisantibodyrecognizesHsp70ofhuman,mouse,rat,rabbit,monkey,guineapig,hamster,chicken,bovine,canine,ovine,porcine,fish,Drosophila,andC.elegansanddoesnotcross-reactwithHsc70.Theepitopeisintheregionofaminoacids436-503ofhumanHsp70.

APPLICATIONS

Immunoblotting:1ug/ml.Abandof70kDaisdetected.

ImmunoblottingofHsp70incelllysatesfromhumancancercelllineswith#11096.

Immunohistochemistry:1-10ug/ml

Immunohistochemicalstainingofinflammatorycellsinhumancolontissuewith#11096.

Immunoprecipitation:1-10ug/ml

ELISA:1-10ug/ml

Flowcytometry:10ug/ml

Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.

Positivecontrol:HeLacelllysate.


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

品牌介绍
QEDBioscience已经设计和制造抗体超过20年,QEDBioscience的目标保持不变:提供市场上最好的抗体产品和服务,并为QEDBioscience的客户提供他们期望的全面的专业知识和帮助。频谱抗体公司如QED。QEDBioscience为我们的学术,生物技术,诊断和药物研究客户开发新型单克隆和多克隆抗体产品。QEDBioscience使用客户的小分子,蛋白质或肽靶标或利用靶CDNA开发这些抗体,是一家提供全方位服务的公司,并提供额外的免疫化学服务,如纯化和结合,以便我们能够为客户提供一种特异于其系统的抗体产品。我们还开发了具有酶中和和抑制受体-配体相互作用以及抗独特型抗体的药理活性的单克隆抗体。