CatalogNo.:11143(clone3H4-2H6)Size:100uginPBS(1mg/ml),pH7.4,50%glycerol,0.09%sodiumazide.

PurifiedbyProteinGaffinitychromatography.

Themolecularchaperonefamilyof90kDaheatshockproteins(Hsp90)isahighlyconservedproteinfamilythatplaysanimportantphysiologicalrole.Hsp90isbestknownforitsassociationwithsignaltransductionprocesses.Tumornecrosisfactorreceptor-associatedprotein1(TRAP1)isarecentlyclonedhomologofHsp90.LikeHsp90,TRAP1isassociatedwithnumerousproteinsthatareinvolvedinmultiplepathways.DataindicatesthatTRAP1isamitochondrialmatrixprotein:itislocalizedinmitochondriaofmammaliancellsandcontainsamitochondrialtargetingpresequence.

Antigen:RecombinanthumanTRAP1

Accessionno.:NP_057376.2

GeneID:10131

HostSpecies:Mouse

AntibodyClass:IgG1

ThisantibodyrecognizeshumanandratTRAP1.Otherspecieshavenotbeeninvestigated.

Immunoblotting:useat1ug/ml.Abandof

~75kDaisdetected.

Positivecontrol:A431celllysateorratbrainlysate.

Thesearerecommendedconcentrations;endusershoulddetermineoptimalconcentrationsfortheirapplications.

DetectionofTRAP1/Hsp75with#11143at1ug/ml.

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notintendedfordiagnosticortherapeuticapplications.