productdatasheet
CatalogNo.:2201
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.
CX3CR1isoneofthechemokinereceptorsthatarerequiredasco-receptorsforHIVinfection.Thegenesencodinghuman,murine,andratCX3CR1havebeenclonedanddesignatedV28andCMKBRL1,CX3CR1,andRBS11,respectively.Thistransmembraneproteinwasrecentlyidentifiedasthereceptorforanoveltransmembranemolecule,fractalkine,andwasrenamedCX3CR1.Recently,CX3CR1wasfoundtoserveasacoreceptorforHIV-1andHIV-2envelopefusionandvirusinfection,whichcanbeinhibitedbyfactalkine.CX3CR1mediatesleukocytemigrationandadhesionandisexpressedinavarietyofhumantissuesandcelllines.
SPECIFICATIONSUMMARYAntigen:Peptidecorrespondingtoaa175-189ofhumanCX3CR1.ThesequenceisidenticaltothatofratCX3CR1anddiffersfromthatofmouseCX3CR1byoneaminoacid.
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide.
Thisantibodyrecognizeshuman,mouseandratCX3CR1(50kD).
Immunoblotting:useat1:500dilution.Positivecontrol:WholecelllysateofTHP-1cells.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures
QEDBioscience,Inc.10919TechnologyPlace,SuiteC
SanDiego,CA92127
TollFree800.929.2114
Phone858.675.2405
Fax858.592.1509
info@qedbio.com
Visitourwebsiteforadditionalproductinformationandtoorderonline.
qedbio.com
