productdatasheet
CatalogNo.:11524(cloneS8b-1)Size:100uginPBS,pH7.4;50%
glycerol,0.09%sodiumazide.PurifiedbyProteinGaffinitychromatography.
IonchannelsareintegralmembraneproteinsthathelpestablishandcontrolthesmallvoltagegrADIentacrosstheplasmamembraneoflivingcellsbyallowingtheflowofionsdowntheirelectRochemicalgradient.Cavβsubunitsareinvolvedinthetransportofthepore-formingalpha1subunittotheplasmamembrane.TheyalsoshieldanERRetentionsignalonthealpha1subunit,therebyguidingthepore-formingsubunittothetargetmembrane.
Antigen:Syntheticpeptidecorrespondingtoaa189-205ofratCavβ2(RSPKPSANSVTSPHSKE)(accessionno.NP_446303).
HostSpecies:Mouse
AntibodyClass:IgG1
Thisantibodyrecognizeshuman,mouse,andratCavβ2.Itdoesnotcross-reactwithCavβ1,Cavβ3,orCavβ4.
APPLICATIONSImmunoblotting:useat1-10ug/ml.Abandof~78kDaisdetected.
AdultratbrainlysateImmunohistochemistryandImmunocytochemistry:useat0.1-1ug/mlImmunofluorescence:useat1-10ug/ml
Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.
Positivecontrol:Ratbrainlysate
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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