CatalogNo.:11565(cloneS178A-9)Size:100uginPBS,pH7.4;50%glycerol,0.09%sodiumazide.PurifiedbyProteinGaffinitychromatography.

IonchannelsareintegralmembraneproteinsthathelpestablishandcontrolthesmallvoltagegrADIentacrosstheplasmamembraneoflivingcellsbyallowingtheflowofionsdowntheirelectRochemicalgradient.Cav3.1isalow-voltage-activatedT-typecalciumchannelexpressedthroughoutthebody.DrugsthatblockT-typecalciumchannelsareusedasantihypertensivesandantiepilepticsandpossIBLyinsomeanestheticsandantipsychotics.

Antigen:Fusionproteincorrespondingtoaa2052-2172(cytoplasmicC-terminus)ofmouseCav3.1(accessionno.

NP_001106284.1).

HostSpecies:Mouse

AntibodyClass:IgG1

Thisantibodyrecognizeshuman,mouse,andratCav3.1.Itdoesnotcross-reactwithCav3.2.

Immunoblotting:useat1-2ug/ml.Abandof>200kDaisdetected.

Immunohistochemistry:useat1-10ug/ml.Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.

Positivecontrol:Ratbrainmembranes.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.