CatalogNo.:56519(cloneS106-20)Size:100uginPBS(1mg/ml),pH7.4,50%glycerol,0.09%sodiumazide.

PurifiedbyProteinGaffinitychromatography.

Ankyrinsareafamilyofadaptorproteinsthatmediatetheattachmentofintegralmembraneproteinstothespectrin-actinbasedmembraneskeleton.Ankyrinshavebindingsitesforthebetasubunitofspectrinandforatleast12familiesofintegralmembraneproteins.Thislinkageisrequiredtomaintaintheintegrityoftheplasmamembranesandtoanchorspecificionchannels,ionexchangers,andiontransportersintheplasmamembrane.

Antigen:Fusionproteincorrespondingto

~1,000C-terminalaminoacidsofhumanAnkyrinG(accessionno.NP_066267.2).HostSpecies:Mouse

AntibodyClass:IgG1

Thisantibodyrecognizeshuman,mouse,andratAnkyrin-G.

Immunoblotting:useat1-2ug/ml.Abandof>200kDaisdetected.

Immunoblotonratbrainmembranes.

Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.

Positivecontrol:ratbrainmembranes.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisproductisstableforatleast1yearat

-20oC.Freezeinmultiplealiquotstoavoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.