productdatasheet

CatalogNo.:28119

Size:100ugProteinGaffinity-purifiedantibodyinPBS,pH7.4.

F-boxproteins,criticalcomponentsoftheconservedubiquitin-proteinligasecomplexSCF(Skp1/Cdc53-Cullin1/F-box),recruitsubstratesforubiquitinationandconsequentdegradationthroughtheirspecificprotein-proteininteractiondomains.NovelhumanF-boxproteinsnamedFBG1,FBG2,FBG3,FBG4and

FBG5constituteasubfamilyofmammalianF-boxproteins.FBGgenesareexpressedinalimitednumberofhumantissuesincludingkidney,liver,brainandmuscletissues.

Immunogen:Syntheticpeptidecorrespondingtoaminoacids268-284ofhumanFBG2.

HostSpecies:RabbitPreservatives:None.Availableonrequest.

Thisantibodyrecognizeshuman,mouse,andratFBG2.

Immunoblotting:useat1-5ug/mldilution.Abandofapproximately34kDaisdetected.Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationfortheirapplications.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.