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CatalogNo.:28120

Size:100ugProteinGaffinity-purifiedantibodyinPBS,pH7.4.

F-boxproteins,criticalcomponentsoftheconservedubiquitin-proteinligasecomplexSCF(Skp1/Cdc53-Cullin1/F-box),recruitsubstratesforubiquitinationandconsequentdegradationthroughtheirspecificprotein-proteininteractiondomains.NovelhumanF-boxproteinsnamedFBG1,FBG2,FBG3,FBG4and

FBG5constituteasubfamilyofmammalianF-boxproteins.FBGgenesareexpressedinalimitednumberofhumantissuesincludingkidney,liver,brainandmuscletissues.

Immunogen:Syntheticpeptidecorrespondingtoaminoacids163-175ofhumanFBG5.

HostSpecies:RabbitPreservatives:None.Availableonrequest.

Thisantibodyrecognizeshuman,mouse,andratFBG5.

Immunoblotting:useat1-5ug/mldilution.Abandofapproximately32kDaisdetected.Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationfortheirapplications.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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