productdatasheet
CatalogNo.:56208
Size:100ugin10mMPBS,pH7.4.
FEN-1(FlapEndonucleaseandFivePrimeExonuclease)isa42kDproteinthatfunctionsasanendonucleasethatcleavesbranchedDNAstructurescontainingsingle-stranded5’flapsorasanexonucleaseonDNAnicksandgaps.FEN-1endonucleaseandexonucleaseactivitiesarestimulatedbyanassociationwithproliferatingcellnuclearantigen(PCNA)inthenucleus.FEN-1appearstohaveimportantrolesinDNAreplicationandrepairandisrequiredincell-freDNAreplicationsystems.
Antigen:RecombinanthumanFEN-1protein(aa1-380)purifiedfrombaculovirus-infectedSf-9cells.
HostSpecies:MouseStABIlizers:NonePreservatives:None.Availableonrequest.
SPECIFICITYThisantibodyrecognizeshumanFEN-1.
Immunoblotting:useat1-5ug/ml.
Positivecontrols:MCF-7cellsandrecombinantfusionprotein.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedure
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