productdatasheet

CatalogNo.:56300

Size:100ugIgGin100ul(1mg/ml)PBS.

Type-AreceptorsfortheneurotransmitterGABA(gamma-aminobutyricacid)areligand-gatedchloridechannelsthatmediateinhibitoryneurotransmission.Acellularprotein,GABA(A)-receptorassociatedprotein(GABARAP),thatinteractswiththegamma2subunitofGABA(A)receptorsandmodulatesreceptorchannelkineticswasrecentlyidentified.GABARAPbindstoGABA(A)receptorsinvitroandinvivo.SequenceanalysisshowssimilaritybetweenGABARAPandlightchain-3ofmicrotubule-associatedproteins1Aand1B.TheinteractionsbetweenGABA(A)receptors,GABARAPandtubulinsuggestamechanismforthetargetingandclusteringofGABA(A)receptors.

Antigen:PeptidederivedfromtheN-terminusofGABARAP.

HostSpecies:Rabbit

Preservatives:0.02%sodiumazide.

ThisantibodyrecognizeshumanGABARAP(14kD).

Immunoblotting:useat1:500-1:1,000dilution.

ELISA:useat1:1,000-1:5,000dilution.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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