productdatasheet
CatalogNo.:2355
Size:100ugIgGin200ulPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.
Interleukin-1(IL-1)andlipopoly-saccharide(LPS)inducecellularresponsesthroughIL-1receptornadToll-likereceptors.IL-1receptor-associatedkinases(IRAKandIRAK2)mediatetheactivationofNF-κBby
IL-1/Tollreceptors,akeystepin
inflammatoryandimmuneresponses.AnovelmemberoftheIRAKfamily,IRAK-M,isadominantnegativemutantofIRAKandinhibitsIL-1orLPSinducedNF-κBactivation.
Antigen:Peptidecorrespondingtoaa581-596ofhumanIRAK-M.
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide.
Thisantibodyrecognizeshuman,mouse,andratIRAK-M(68kD).Nocross-reactivitywithIRAKorIRAK2.
Immunoblotting:useat1:500-1:1,000dilution.
Positivecontrol:Tissuelysatefrommousespleenorratkidney.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures
QEDBioscience,Inc.10919TechnologyPlace,SuiteC
SanDiego,CA92127
TollFree800.929.2114
Phone858.675.2405
Fax858.592.1509
info@qedbio.com
Visitourwebsiteforadditionalproductinformationandtoorderonline.
qedbio.com
