productdatasheet
CatalogNo.:56210
Size:100ulpurifiedantibodyinPBS,pH7.4.
JAB-1isa38kDproteinwhichwasoriginallydescribedasacoactivatorforcJUN.Itispresentinalargeproteincomplexcalledthe“signalosome”whichhasbeenproposedtoplayasignalingroleinmammaliancells.ThisproteincomplexappearstobeanalogoustotheCOP9complexinplantswhichplaysanimportantroleinlight-mediatedplantdevelopment.AlthoughthespecificfunctionofJAB-1isunclear,itappearstobeinvolvedintargetingproteinsfordegradationbytheproteasome.
Antigen:MouseJAB-1gst-fusionprotein(aa1-334)expressedinE.coli.HostSpecies:Mouse
StABIlizers:NonePreservatives:None.Availableonrequest.
SPECIFICITYThisantibodyrecognizeshumanandmouseJAB-1.
ImmunoblottingandImmuno-precipitation:useat0.5-1ug/ml.
Positivecontrols:293cellsandrecombinantfusionprotein.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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