productdatasheet
CatalogNo.:56114
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.
Antigen:Peptidecorrespondingtoaa712-727ofhumanNAK/TBK1.ThissequenceisidenticaltothatofmouseNAK/TBK1.
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide
ThisantibodyrecognizesanepitopeattheC-terminusofhuman,mouse,andratNAK/TBK1(NF-κBActivatingKinaseandTANK-BindingKinase1).NAK/TBK1activatesIKKβthroughdirectphosphorylationandactivatesNF-κBaswellinresponsetogrowthfactors.NAK/TBK1functionsupstreamofNIKandtheIKKcomplexandiscriticalinprotectingembryonicliverfromapoptosis.Thisantibodydoesnotcross-reactwithIKKα,IKKβ,IKKε,orIKKγ.
Immunoblotting:useat0.5-1ug/ml.Inimmunoblots,abandof84kDisdetected.
Positivecontrol:MOLT4celllysate.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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