CatalogNo.:56525(cloneS308-48)Size:100uginPBS(1mg/ml),pH7.4,50%glycerol,0.09%sodiumazide.

PurifiedbyProteinGaffinitychromatography.

TheNMDAreceptor(NMDAR),aglutamatereceptor,isthepredominantmoleculardeviceforcontrollingsynapticplasticityandmemoryfunction.NMDARisaheterotetrameroftwoNR1andtwoNR2subunits.MultiplereceptorisoformswithdistinctbraindistributionsandfunctionalpropertiesarisebyselectivesplicingoftheNR1transcriptsand

differentialexpressionoftheNR2subunits.

Antigen:Fusionproteincorrespondingtoaa42-361(extracellularN-terminus)ofratNR1(accessionno.NP_058706.1).

HostSpecies:Mouse

AntibodyClass:IgG1

Thisantibodyrecognizeshuman,mouse,andratNR1.

Immunoblotting:useat1-2ug/ml.Abandof~105kDaisdetected.

Immunoblotonratbrainmembranes.

Immunohistochemistry:useat1-5ug/ml.Thesearerecommendedconcentrations.Endusershoulddetermineoptimalconcentrationsfortheirapplications.

Positivecontrol:Ratbrainmembranes.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Thisproductisstableforatleast1yearat

-20oC.Freezeinmultiplealiquotstoavoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.