productdatasheet
Catalogno.:11081
Size:100ulwholeantiserum
AmicrosomalenzymeknownasProteinDisulfideIsomerase(PDI)isinvolvedintheformationofdisulfidebondsinmanyextracellularproteinsthroughitsoxidaseandisomeraseactivities.Itisalsoinvolvedinthereductionofdisulfidebondsinproteins.PDIislocatedprimarilyintheendoplasmicreticulum(ER)butmayalsobefoundinthecytosol.PDIcanresideintheERduetothehighlyconservedKDELsequenceatitscarboxyterminuswhichservesasanER-retentionsignal.
Antigen:SyntheticpeptidederivedfromratPDIconjugatedtoKLH.HostSpecies:Rabbit
Subclass:IgG
StABIlizers:NonePreservatives:None.Availableonrequest.
SPECIFICITYThisantibodyrecognizeshuman,monkey,mouse,rat,hamster,bovine,ovine,porcine,canine,guineapig,andXenopusPDI.
Westernblot:Useat1:4,000dilution.Abandofapprox.58kDisdetected.
Immunocytochemistry/Immunohisto-chemistry:Useat2-5ug/ml.
Immunoprecipitation:Useat10ug/ml.
DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.
Storefrozenproductatorbelow-20oC.Foroptimalstorage,aliquottosmallerportionsandstoreat-20oCto-70oC.Avoidrepeatedfreeze/thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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Phone858.675.2405
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