ORDERINGINFORMATION
CatalogNo.:19701(cloneB38)Format:250ugProteinG-purifiedantibodyinPBS,pH7.4BACKGROUND
CoagulationcofactorV(FactorV)isahighmolecularweightglycoproteinthatperformsseveralcriticalfunctionsinregulatinghemostasis.Initsthrombin-activatedform(FVa)itinteractswithFactorXaandCa+2toformtheprothrombinasecomplex.ThiscomplexcatalyzestheformationofthrombinfromprothrombinatratessubstantiallyhigherthanFactorXaalone.
SPECIFICATIONSUMMARY
Antigen:PurifiedhumanFactorV.HostSpecies:MouseAntibodyClass:IgG1Specificity:ThisantibodyrecognizestheF1F2polypeptideofhumanFactorValightchain.APPLICATIONS
Westernblotting:abandofapprox.74kDaisdetected.
DILUTIONINSTRUCTIONS
DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.
STORAGEANDSTABILITY
Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
PRODUCTREFERENCES
GewirtzAMetal.1986Blood67:1639-1648.
AnnamalaiAEetal.1987Blood70:139-156.
Forinvitroinvestigationaluseonly.Notintendedfortherapeuticordiagnosticapplications.
