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QED Bioscience/Recombinant Human Annexin A9/13823P-10/1 Ea
ADVANCEDRESEARCHTECHNOLOGIES
CatalogNumber | Size |
13823P-2 | 2ug |
13823P-10 | 10ug |
13823P-1000 | 1000ug |
Formulation:Sterile-filteredcolorlesssolutionin10mMTris,pH8.0,0.1%TritonX-100,and0.002%sodiumazide.Purifiedbyproprietarychromatographictechniques.
BACKGROUND
Theannexinsareafamilyofcalcium-dependentphospholipids-bindingproteins.Membersofthisfamilycontain4internalrepeatdomains,eachofwhichincludesatypeIIcalcium-bindingsite.
Thesecalcium-bindingsitesarerequiredforannexinstoaggregateandcooperativelybindanionicphospholipidsandextracellularmatrixproteins.ThemoststrikingfeatureofAnnexinA9isacompleteablationofallfourhomologoustypeIIcalcium-bindingsitesintheconservedtetradcore.AlthoughallfoursitesinAnnexinA9containaminoacidsubstitutionsthatablatedtheirfunction,theconservedionchannelformedbythetetradcoreisintact.
DESCRIPTION
RecombinantHumanAnnexinA9producedinE.coliisasingle,non-glycosylatedpolypeptidechaincontainingaminoacids1-339withamolecularweightof38.9kDa.ItincludesaT7tagattheN-terminus.
SPECIFICATIONSUMMARY
Source:EscherichiacoliPurity:Greaterthan95%asdeterminedbySDS-PAGE.Accessionnumber:O76027
STORAGEANDSTABILITY
Althoughstableat4oCfor1week,productisbeststoredatorbelow-20oC.Forlongtermstorage,additionofacarrierprotein(0.1%HSAorBSA)isrecommended.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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