productdatasheet
CatalogNumber | Size |
24000P-20 | 20ug |
24000P-100 | 100ug |
24000P-1000 | 1000ug |
CatalogNumber | Size |
24000P-20 | 20ug |
24000P-100 | 100ug |
24000P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredsolutionin150mMNaCl,10mMsodiumphosphate,pH7.0,and0.05%sodiumazide.
Purifiedbyproprietarychromatographictechniques.
Troponinisafundamentalregulatoryproteinofstriatedmusclecontraction,and,togetherwithtropomyosin,ispositionedontheactinfilament.
Troponinhas3subunits:TnI,theinhibitorofactomyosinATPase,TnT,whichcontainsthebindingsitefortropomyosin,andTnC,theproteinencodedbytheTNNC1gene.BindingofcalciumtoTnCstopstheinhibitoryactionofTnI,allowingtheinteractionofactinwithmyosin,thehydrolysisofATP,andthegenerationoftension.
MutationsintheTNNC1genearelinkedtocardiomyopathydilatedtype1Z.
RecombinantHumanTnCproducedin
E.coliisasingle,non-glycosylatedpolypeptidechainwithamolecularweightof18kDa.
Source:Escherichiacoli
Purity:Greaterthan95%asdeterminedbySDS-PAGEandRP-HPLC.
Accessionnumber:P63316
Althoughstableatroomtemperaturefor3weeks,productisbeststoredat4oC.Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlong-termstorage.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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SanDiego,CA92127
TollFree800.929.2114
Phone858.675.2405
Fax858.592.1509
info@qedbio.com
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