productdatasheet
CatalogNumber | Size |
24001P-10 | 10ug |
24001P-50 | 50ug |
24001P-1000 | 1000ug |
CatalogNumber | Size |
24001P-10 | 10ug |
24001P-50 | 50ug |
24001P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredsolutionin50mMTris,pH8.0and6Murea.
Purifiedbyproprietarychromatographictechniques.
TroponinI(TnI)troponinT(TnT)andtroponinC(TnC)formthetroponincomplexofthinfilamentsofstriatedmuscle.TnIactsastheinhibitorysubunitbyblockingactin-myosininteractionsandtherebymediatingstriatedmusclerelaxation.TheTnIsubfamilyconsistsof3genes:TnI-skeletal-fast-twitch,TnI-skeletal-slow-twitch,andTnI-cardiac.TheTNNI3geneencodestheTnI-cardiacproteinandisexclusivelyexpressedincardiacmuscletissue.MutationsintheTNNI3genecausefamilialhypertrophiccardiomyopathytype7andfamilialrestrictivecardiomyopathy.
RecombinantHumanTnIproducedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining165aminoacidswithamolecularweightof24kDa.
Source:Escherichiacoli
Purity:Greaterthan98%asdeterminedbySDS-PAGEandRP-HPLC.
Accessionnumber:P19429
Althoughstableat4oCfor1week,productisbeststoredatorbelow-20oC.Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlong-termstorage.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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