productdatasheet
CatalogNumber | Size |
26103P-5 | 5ug |
26103P-20 | 20ug |
26103P-1000 | 1000ug |
CatalogNumber | Size |
26103P-5 | 5ug |
26103P-20 | 20ug |
26103P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredsolutionin20mMTris-HCl,pH8.0,and10%glycerol.Purifiedbyproprietarychromatographictechniques.
ChromograninA(CHGA)isamemberoftheneuroendocrinesecretoryproteinfamilylocatedinsecretoryvesiclesofneuronsandendocrinecells.CHGAisaprecursortothreeBIOLOGicallyactivepeptides:vasostatin,pancreastatin,andparastatin.Thesepeptidesfunctionasautocrineorparacrinenegativemodulatorsoftheneuroendocrinesystem.Otherpeptidesincludingchromostatin,betagranin,WE-14andGE-25arealsoderivedfromfull-lengthCHGA.CHGAhasnumerousbiologicalactivitiesincludingantifungalandantimicrobialaction,modulationofcelladhesion,andinhibitionofparathyroidhormonesecretion.
RecombinantHumanCHGAproducedinE.coliisasinglenon-glycosylatedpolypeptidechaincontaining114aminoacids(aa19-131)withamolecularweightof12.8kDa.
Source:EscherichiacoliPurity:Greaterthan95%asdeterminedbySDS-PAGE.Accessionnumber:P10645Aminoacidsequence:
MLPVNSPMNKGDTEVMKCIVEVISDTLSKPSPMPVSQECFETLRGDERILSILRHQNLLKELQDLALQGAKERAHQQKKHSGFEDELSEVLENQSSQAELKEAVEEPSSKDVME.
Storeat4oCifentirevialwillbeusedwithin2-4weeks.Storeatorbelow
-20oCforlongerperiodsoftime.
Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlong-termstorage.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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