CatalogNo.:45101

Size:20ug

Source:Genetically-engineeredE.coli.

MolecularWeight:15,000daltons

Purity:>90%

Dilutewitheither0.1%TFA/40%acetonitrileorPBS/0.1%CHAPSforbeststABIlityandtopreventabsorptionofproductonwallsofcontainers.

Thisproductisstableforatleastone(1)

oo

Diluent:0.1%trifluoroaceticacid+40%acetonitrile.

Preservatives:None

PurifiedbyheparinaffinitychromatographyandHPLC;singlebandat1ugonsilver-stainedSDS-PAGE.

TheactivityofacidicFGFat1-10ng/mlisdeterminedbyacellularproliferationassayusingmousefibroblasts.Theoptimalconcentrationofthisproductforusewithothercelltypesmustbedeterminedbytheenduser.

Inthepresenceofheparin,45101bindstomostcellsthatexpressFGFreceptor;bindstoallknownisoformsofFGFreceptor.

yearat-20Cto-70C.Keepfrozen

untiluse.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.

Burgess,WHandMaciag,T(1989)AnnualRevBoichem58:575.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

MaterialSafetyDataSheetRecombinantHumanAcidicFGF1(productno.45101)

Thisproductisforinvitroinvestigationaluseonlyandisnotintendedfortherapeuticordiagnosticprocedures.

Theinformationbelowisbelievedtobecorrectbutdoesnotpurporttobeallinclusiveandshallbeusedonlyasaguide.QEDBioscienceshallnotbeliableforanydamageresultingfromhandlingorfromcontactwiththeaboveproduct.

HazardousIngredients

Thephysical,chemical,andtoxicologicalpropertiesofthesecomponentshavenotbeenfullyinvestigated.Itisrecommendedthatalllaboratorypersonnelfollowstandardlaboratorysafetyprocedureswhenhandlingthisproduct.SafetyproceduresshouldincludewearingOSHAapprovedsafetyglasses,gloves,andprotectiveclothing.Directphysicalcontactwiththeproductshouldbeavoided.

PhysicalData

Thisproductconsistsofpurifiedproteinshippedondryice.Thephysicalpropertiesofthisproducthavenotbeenthoroughlyinvestigated.

FireandExplosionHazardandReactivityData

Theinformationbelowdescribesthefollowingcomponentsinanundilutedstate:

Trifluoroaceticacid

Non-flammable,non-explosive,stableunderrecommendedstorageconditions.

Acetonitrile

Flammableliquid,vaporsmayformexplosivemixturewithair,stableunderrecommendedstorageconditions.

ToxicologicalProperties

Maybeharmfulbyinhalation,ingestion,orskinabsorption.Thetoxicologicalpropertiesofthisproducthavenotbeenthoroughlyinvestigated.Avoidcontactwithskinandeyes.Avoidinhalationoringestion.

PreventativeMeasures

WearchemicalsafetygogglesandcompatIBLechemical-resistantgloves.Avoidinhalation,ingestion,contactwitheyes,skin,orclothing.

SpillandLeakProcedures

Observeallfederal,state,andlocalenvironmentalregulations.

Wearprotectiveequipment.

Absorbonsandorvermiculiteandplaceinclosedcontainersfordisposal.Contactalicensedprofessionalwastedisposalservicetodisposeofthismaterial.

FirstAidMeasures

Ifinhaled,movepersonintofreshairandconsultaphysician.

Incaseofskincontact,washcontactedareawithsoapandwaterandconsultaphysician.

Incaseofeyecontact,rinseeye(s)thoroughlywithwaterforatleast15minutesandconsultaphysician.

Ifswallowed,donotinducevomiting.Nevergiveanythingbymouthtoanunconsciousperson.Rinsemouthwithwaterandconsultaphysician.