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QED Bioscience/Recombinant Human GroEL (Hsp60)/11100P-1000/1 Ea
productdatasheet
CatalogNumber | Size |
11100P-5 | 5ug |
11100P-20 | 20ug |
11100P-1000 | 1000ug |
CatalogNumber | Size |
11100P-5 | 5ug |
11100P-20 | 20ug |
11100P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredcolorlesssolutioncontains25mMTris-HCl,pH7.5,100mMNaCl,5mMDTT,and10%
glycerol.Purifiedbyproprietarychromatographictechniques.
BACKGROUND
Hsp60isamitochondrialchaperoninresponsIBLefortransportationandrefoldingofproteinsfromthecytoplasmdirectlyintothemitochondrialmatrix.
Hsp60isregulatedbytheHsp10co-chaperonin.Hsp10coordinatestheATPaseactivityoftheHsp60subunitsinordertoallowthereleaseofboundpolypeptideinamannerthatisproductiveforitscorrectfolding.
RecombinantHumanGroEL(Hsp60)producedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining553aminoacidswithamolecularweightof63kDa.
Source:Escherichiacoli
Purity:Greaterthan95%asdeterminedbySDS-PAGEandRP-HPLC.
Accessionnumber:P10809
AminoAcidSequence:
MGSSHHHHHHSSGLVPRGSHMLRLPTVFRQMRPVSRVLAPHLTRAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGMKFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSIQSIVPALEIANAHRKPLVIIAEDVDGEALSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKRIQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLTPANEDQKIGIEIIKRTLKIPAMTIA
KNAGVEGSLIVEKIMQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLTTAEVVVTEIPKEEKDPGMGAMGGMGGGMGGGMF
Storeat4oCifentirevialwillbeusedwithin2-4weeks.Storeatorbelow
-20oCforlongerperiodsoftime.For
longtermstorage,additionofacarrierprotein(0.1%HSAorBSA)isrecommended.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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Phone858.675.2405
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info@qedbio.com
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