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QED Bioscience/Recombinant Human Hsp90 alpha/11102P-1000/1 Ea
RecombinantHumanHsp90alpha
CatalogNumber | Size |
11102P-5 | 5ug |
11102P-20 | 20ug |
11102P-1000 | 1000ug |
CatalogNumber | Size |
11102P-5 | 5ug |
11102P-20 | 20ug |
11102P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredcolorlesssolution(1mg/ml)in20mMTris-HCl,pH
7.4and100mMNaCl.Purifiedbyproprietarychromatographictechniques.
Hsp90,amammalianheatshockprotein,isamolecularchaperonethathelpstokeepatargetproteininafolding-competentstate.Ithasbeenfoundincellcytosol,nucleus,andendoplasmicreticulumofmanydifferenttissues.
Hsp90functionsasadimer.IthasanATP-bindingsiteandlowATPaseactivity.Itschaperoneactivityisenhancedathightemperatures,anditsfunctionissensitivetobivalentcationconcentrations.
RecombinanthumanHsp90producedin
E.coliisasingle,non-glycosylatedpolypeptidecontaining732aminoacidswithamolecularweightof86.8kDa.ItisexpressedwithanN-terminal6XHis-tag.Accessionno.:P07900.5.
Purity:>90%asdeterminedbyRP-HPLCandSDS-PAGE.
AMINOACIDSEQUENCEMGSSHHHHHHSSGLVPRGSHMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVSDDEAEEKEDKEEEKEKEEKESEDKPEIEDVGSDEEEEKKDGDKKKKKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMPPLEGDDDTSRMEEVD
Storeat4oCifentirevialwillbeusedwithin2-4weeksofreceipt.Storeatorbelow-20oCforlongerperiodsoftime.Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlongterm-storage.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.
