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QED Bioscience/Recombinant Human HspA5 (Hsp70 protein 5)/11117P-2/1 Ea
RecombinantHumanHspA5(Hsp70protein5)
CatalogNumber | Size |
11117P-2 | 2ug |
11117P-10 | 10ug |
11117P-1000 | 1000ug |
CatalogNumber | Size |
11117P-2 | 2ug |
11117P-10 | 10ug |
11117P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredcolorlesssolution(1mg/ml)in20mMTris-Hcl,pH8.0,2mMDTT,200mMNaCl,10%
glycerol.Purifiedbyproprietarychromatographictechniques.
HspA5,amemberoftheHsp70family,playsaroleinfoldingandassemblingofproteinsintheendoplasmicreticulumbymonitoringproteintransportthroughthecell.HspA5isastressresponseproteinthatisinducedbyconditionsthatadverselyaffectendoplasmicreticulumfunction.HspA5isessentialtomaintenanceofcellhomeostasisandpreventionofapoptosis.
RecombinanthumanHspA5producedinE.coliisasingle,glycosylatedpolypeptidecontaining640aminoacids(aa20-650)withamolecularweightof71kDa.Itisfusedtoan8-aminoacidHis-tagattheC-terminus.
SPECIFICATIONSUMMARYSource:EscherichiacoliPurity:Greaterthan90%asdeterminedbySDS-PAGE.Accessionnumber:P11021.2Aminoacidsequence:
MEEDKKEDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQHQARIEIESFYEGEDFSETLTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNGKEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGIETVGGVMTKLIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRGVPQIEVTFEIDVNGILRVTAEDKGTGNKNKITITNDQNRLTPEEIERMVNDAEKFAEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEEDTAELEHHHHHH.
Storeat4oCifentirevialwillbeusedwithin2-4weeks.Storeatorbelow-20oC
forlongerperiodsoftime.Additionofacarrierprotein(suchas0.1%HSAorBSAisrecommendedforlong-termstorage.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
