productdatasheet
CatalogNumber | Size |
11124P-5 | 5ug |
11124P-25 | 25ug |
11124P-1000 | 1000ug |
CatalogNumber | Size |
11124P-5 | 5ug |
11124P-25 | 25ug |
11124P-1000 | 1000ug |
ORDERINGINFORMATION
Formulation:Sterile-filteredcolorlesssolutionin20mMTris-HCl,pH8.0,and50mMNaCl.Purifiedbyproprietarychromatographictechniques.
HspH1isamemberofthemammalianHsp105/110family,asubgroupoftheHsp70family.TwoisoformsofHspH1,alphaandbeta,havebeenidentified.HspH1associateswithHsp70/Hsc70ascomplexesandnegativelyregulatesthechaperoneactivityofHsp70/Hsc70invivoandinvitro.HspH1ishighlyexpressedinmanyhumantumors.
RecombinanthumanHspH1producedinE.coliisasingle,non-glycosylatedpolypeptidecontaining894aminoacidswithamolecularweightof100kDa.ItisexpressedwithaHis-tagattheN-terminus.
Source:Escherichiacoli
Purity:Greaterthan90%asdeterminedbySDS-PAGEandRP-HPLC.
Accessionnumber:Q92598
Aminoacidsequence:MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSMSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIY
KQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEA
VARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKNSVNMDLD.
Storeat4oCifentirevialwillbeusedwithin2-4weeks.Storeatorbelow-20oCforlongerperiodsoftime.Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlong-termstorage.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
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