RecombinantHumanMyelinOligodendrocyteGlycoprotein(MOG)
CatalogNumber | Size |
24202P-10 | 10ug |
24202P-50 | 50ug |
24202P-1000 | 1000ug |
CatalogNumber | Size |
24202P-10 | 10ug |
24202P-50 | 50ug |
24202P-1000 | 1000ug |
ORDERINGINFORMATION
MyelinOligodendrocyteGlycoprotein(MOG)isamembraneproteinexpressedontheoligodendrocytecellsurfaceandtheoutermostsurfaceofmyelinsheaths.Givenitslocalization,itisaprimetargetantigenofimmune-mediateddemyelination.MOGisinvolvedincompletionandmaintenanceofthemyelinsheathandincell-cellcommunication.
MOGisdifferentiallyexpressedinthedorsolateralprefrontalcortexandinthetemporallobefrompatientswithschizophrenia.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.
DESCRIPTIONRecombinantHumanMOGproducedin
E.coliisasinglenon-glycosylatedpolypeptidechaincontaining132aminoacidswithamolecularweightof15.2kDa.Itisfusedtoa6XHis-tag
attheC-terminus.
AminoAcidSequence:Met-GQFRVIGPRHPIRALVGDEVELPCRISPGKNATGMEVGWYRPPFSRVVHLYRNGKDQDGDQAPEYRGRTELLKDAIGEGKVTLRIRNVRFSDEGGFTCFFRDHSYQEEAAMELKVEDPFYWVSPG-HHHHHH
Purity:Greaterthan95%asdeterminedbySDS-PAGEandRP-HPLC.Accessionnumber:Q16653ReconstitutelyophilizedMOGinsterile10mMaceticacidtonolessthan100ug/mlwhichcanbefurtherdilutedinotheraqueoussolutionsasneeded.
Althoughstableatroomtemperaturefor3weeks,thelyophilizedproductisbeststoredatorbelow-20oC.Uponreconstitution,MOGcanbestoredat4oCforupto1weekbutisbeststoredatorbelow-20oCforlongerperiodsoftime.
Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlong-termstorage.
