CatalogNo.Size
50192P-22ug
50192P-1010ug
50192P-5050ug
50192P-100100ug
50192P-10001000ug
CCL14,alsoknownasHemofiltrateCCChemokine-1(HCC-1)isasmallcytokine(~8kDa)thatisconstitutivelyexpressedinmultipletissues.UponprocessingoftheN-terminalresiduesoffull-lengthHCC-1bytheuPA-plasminsystem,theactiveformofHCC-1isastrongagoNISTforCCR1,CCR5,and,toalesserextent,CCR3.CCL14causeschemotaxisofdifferenttypesofleukocytes,anditsactiveformisapotentinhibitorofHIVentry.
Source:RecombinanthumanCCL14isproducedinE.coli(accessionno.
Q16627,aa28-93).
ProteinSequence:GPYHPSECCFTYTTYKIPRQRIMDYYETNSQCSKPGIVFITKRGHSVCTNPSDKWVQDYIKDMKEN
MolecularMass:7.801kDabyMassSpec.
Purity:>97%bySDS-PAGE
Activity:EC50=0.1-0.4nMdeterminedbyMigrationAssayincellsexpressingCCR1.
EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.
Form:Lyophilized.
CarrierProtein:None.
Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.
StABIlityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.
1month,-20oCto-70oC,understerileconditionsafterreconstitution.Bestifusedimmediatelyafterreconstitution.
Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.
