CatalogNo.Size#1112Anti-HumanCCR5Antibody50187P-22ug

50187P-1010ug

50187P-5050ug

50187P-100100ug

50187P-10001000ug

CCL3,alsoknownasMacrophageInflammatoryProtein-1α(MIP-1α),isaproinflammatorychemokinethatstimulateschemotaxisandactivationofdifferentcellpopulationsoftheimmunesystem.CCL3bindstoCCR1,CCR4,andCCR5receptors,anditisoneofthemajorHIV-suppressivefactorsproducedbyCD8+T-cells.CCL3inducesdose-dependentinhibitionofdifferentstrainsofHIV-1,HIV-2,andsimianimmunodeficiencyvirus(SIV).

Source:RecombinanthumanCCL3isproducedinE.coli(accessionno.

P10147).

ProteinSequence:SLAADTPTACCFSYTSRQIPQNFIADYFETSSQCSKPGVIFLTKRSRQVCADPSEEWVQKYVSDLELSA

MolecularMass:7.716kDabyMassSpec.

Purity:>97%bySDS-PAGE

Activity:EC50=0.2nMdeterminedbymigrationofrecombinantCCR5-expressingcells.

EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.

Form:Lyophilized.

CarrierProtein:None.

Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.

StABIlityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.

1month,2oCto8oC,understerileconditionsafterreconstitution.

3months,-20oCto-70oC,understerileconditionsafterreconstitution.

Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.