
RecombinantCCL27(CTACK)
CatalogNo.Size
50182P-22ug
50182P-1010ug
50182P-5050ug
50182P-100100ug
50182P-10001000ug
CCL27,alsoknownasCutaneousT-cell-attractingChemokine(CTACK)isaligandforcellsurfacereceptorCCR10.ItisresponsIBLeforchemotaxisofskin-homingmemoryT-cellsduringcutaneousinflammation.Interestingly,afterCCR10-mediatedinternalization,CCL27,aswellasanon-secretedsplicevariantofthesamegene,canreachthenucleusandmodulatetranscriptionandcellbehavior.
DESCRIPTIONDESCRIPTIONSource:RecombinanthumanCCL27,producedinE.coli,correspondstoaa25-112(accessionno.Q9Y4X3).
ProteinSequence:FLLPPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNPSLSQWFEHQERKLHGTLPKLNFGMLRKMG
MolecularMass:10.149kDabyMassSpec.
Purity:>97%
Activity:EC50=34nMdeterminedbyMigrationAssayinL1.2cellsexpressingCCR10.
EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.
Form:Lyophilized.
CarrierProtein:None.
Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.
StABIlityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.
1month,2oCto8oC,understerileconditionsafterreconstitution.
3months,-20oCto-70oC,understerileconditionsafterreconstitution.
Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.