CatalogNo.Size#1112Anti-HIVCo-ReceptorCCR5Antibody50181P-22ug

50181P-1010ug

50181P-5050ug

50181P-100100ug

50181P-10001000ug

CCL5,alsoknownasRegulatedonActivation,NormalT-cellExpressedandSecreted(RANTES),isaproinflammatorychemokinethatinducesmigrationandactivationofleukocytes,andisalsoimpliedinHIVinfection.CCL5bindstocellsurfacereceptorsCCR1,CCR3,CCR4,andCCR5.

ItsBIOLOGicaleffectsonleukocyteactivationandHIVinfectionsisdependentuponconcentrationandonthebindingofcellsurfaceglycosaminoglycans.

Source:RecombinanthumanCCL5,producedinE.coli,correspondstoaa24-91(accessionno.P13501).

ProteinSequence:SPYSSDTTPCCFAYIARPLPRAHIKEYFYTSGKCSNPAVVFVTRKNRQVCANPEKKWVREYINSLEMS

MolecularMass:7.851kDabyMassSpec.

Purity:>97%

Activity:EC50=0.13nMdeterminedbyMigrationAssayinL1.2cellsexpressingCCR5.

EndotoxinLevel:<0.01EUper1ugofproteinbyLALmethod.

Form:Lyophilized.

CarrierProtein:None.

Reconstitution:Recommendedat100ug/mlinsteriledistilledwater.

StABIlityandStorage:12monthsfromdateofreceipt,-20oCto-70oC,assupplied.

1month,2oCto8oC,understerileconditionsafterreconstitution.

3months,-20oCto-70oC,understerileconditionsafterreconstitution.

Forinvitroinvestigationaluseonly.Notforuseindiagnosticortherapeuticprocedures.