product data sheet

Catalog No.: 56210

Size: 100ul purified antibody in PBS, pH 7.4.

JAB-1 is a 38 kD protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the \"signalosome” which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants which plays an important role in light-mediated plant development. Although the specific function of JAB-1 is unclear, it appears to be involved in targeting proteins for degradation by the proteasome.

Antigen: Mouse JAB-1 gst-fusion protein (aa 1-334) expressed in E. coli. Host Species: Mouse

Stabilizers: None Preservatives: None. Available on request.

This antibody recognizes human and mouse JAB-1.

Immunoblotting and Immuno- precipitation: use at 0.5-1 ug/ml.

Positive controls: 293 cells and recombinant fusion protein.

Dilute in PBS or medium which is identical to that used in the assay system.

This antibody is stable for at least one

(1) year at -20oC. Avoid multiple freeze- thaw cycles.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.

QED Bioscience, Inc. 10919 Technology Place, Suite C

San Diego, CA 92127

Toll Free 800.929.2114

Phone 858.675.2405

Fax 858.592.1509

info@qedbio.com

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